About us
Dr. Oran Piamkulvanich
Founder and Chief Executive Officer of Wincell Research Co., Ltd.
There is a high number of cancer patients in Thailand, and it tends to increase continuously. The young generations’ recent lifestyle is one of the significant factors in weakening their immune system, leading to a high risk of unconsciously being diseased. I am always motivated to develop and keep applying our knowledge and know-how in medical technologies to heal degenerative diseases caused by cancers and infections. A team of professional researchers from Wincell Research is ready for initiation and cooperation to achieve our mission of utilizing advanced medical biotechnology in culturing and activating immune cells for treating patients at an international standard level.
Cancer vaccine : A hope for cancer patients
A team of experts from the Osaka University’s Medical Institute, Japan, led by Professor Dr. Haruo Sugiyama, has approved granting Wincell Research the exclusive license to provide clients in Thailand with his invented and licensed cancer vaccine outside of Japan. Wincell Research will have the right to access and implement knowledge, technology, and various innovations related to the cancer vaccine mentioned. It is as if you were traveling to Japan to receive cancer vaccine services. The concept of this cancer vaccine technology is to activate immune cells to learn and recognize cancer cells, leading to a prompt response of the immune system to eliminate cancer cells and prevent their invasion. The technology is equipped with culturing and multiplying antigen-presenting immune cells known as dendritic cells (DCs) collected from clients’ blood samples and stimulating them with the most prevalent cancer antigen, Wilms tumor protein 1 (WT1), under laboratory conditions before administering them back to clients. The WT1 tumor protein was chosen as a stimulant because it is an antigen found dominantly in most types of cancer. The team of experts from Japan has studied, researched, and found specific sites on WT1 that can bind well with DCs, which is a discovery that was patented by the European Patent Office in 2001. After stimulating DCs with WT1, they present this cancer antigen on their surface and transmit this information to T cells in the lymph nodes. T cells learn and recognize cancer cells and effectively eliminate them. T cells are immune cells that play a crucial role in the specific or adaptive immune system. When cancer cells arise in the body, T cells that have learned through the cancer vaccine mechanism are ready to act promptly to destroy the cancer cells, inhibiting the cancer cells from having the opportunity to increase in number or spread further. This cancer vaccine technology has been provided to more than ten thousand cases and found to be safe and efficient for treating and enhancing the cancer patient’s quality of life.
Signing a memorandum of agreement for research and development
The Wincell Research Co., Ltd. team led by Dr. Oran Piamkulvanich, the Founder and CEO of Wincell Research Co., Ltd.) joined the Faculty of Medicine Siriraj Hospital – Mahidol University (MU) led by Prof. Dr. Apichat Asavamongkolkul (Dean of Faculty of Medicine Siriraj Hospital – MU) as a chairperson along with Assoc. Prof. Dr. Sith Sathornsumetee (Vice Dean of Research and Innovation, Faculty of Medicine Siriraj Hospital – MU) and Prof. Dr. Pa-thai Yenchitsomanus (Director of Siriraj Center of Research Excellence for Cancer Immunotherapy or SiCORE-CIT) to sign a memorandum of agreement. The signing ceremony was held at meeting room 101, His Majesty The King 80th Birthday Anniversary 5th December 2007 (SiMR) Building, 1st Floor, Siriraj Hospital. Read more
Joining and publishing a research article in "Food Science & Nutrition" journal
Wincell Research collaborated with researchers from Mahidol University and Asian Phytoceuticals Public Co., Ltd. on a project, “Efficacy of a dietary supplement derived from five edible plants on telomere length in Thai adults: A randomized, double-blind, placebo-controlled trial.” The research outcomes were published in the international journal, “Food Science & Nutrition.” Read more
Launching the cancer risk assessment service
Wincell Research has created a cancer risk assessment service by linking lifestyle information through the client response to behavioral questionnaires with analytical results from the medical diagnostic laboratory. This service will offer clients awareness of their cancer risk and a health improvement advisory/guideline to reduce that risk with the concept, “Knowing your risk fast and in time; you can stay away from cancer.”
Providing stem cells for research use
Wincell Research supports stem cells for use in a research study entitled, “An efficacy study of mesenchymal stem cells from human umbilical cord tissue for the treatment of feline chronic kidney disease,” which was conducted at the School of Anti-Aging and Regenerative Medicine, Mae Fah Luang University. Read more
Certified with ISO 9001
Wincell Research has implemented a management and operational system following the International Organization for Standardization (ISO) and has been certified with ISO 9001 since then.
Registered modern drug manufacturing facility
Wincell Research has passed the inspection of the Thai Food and Drug Administration for registration as a modern drug manufacturing facility.
Licensed cancer vaccine technology from Japan
A team of experts from Japan, led by Professor Dr. Haruo Sugiyama of the Osaka University Medical Institute, has signed an approval granting Wincell Research the exclusive license to provide their invented cancer vaccine outside of Japan. This cancer vaccine was developed and patented in 2001. Wincell Research will have the right to access and implement knowledge and know-how involved with this cancer vaccine directly from Japan for offering the service in Thailand.
"Prototype" of the cell culture laboratory blueprint
The Thai Food and Drug Administration has inspected, evaluated, and approved the laboratory blueprint of Wincell Research as the “prototype” of the laboratory blueprint that follows the criteria and standards of Good Manufacturing Practice (GMP) in cell culture.
Amnion membrane-derived stem cells
Wincell Research started offering the cultivation service of “amnion membrane-derived mesenchymal stem cells” for the first time in 2016. These stem cells play a crucial role in regenerative medicine and have been used worldwide for healing various degenerative conditions or diseases in patients.
Telomere length, fibroblasts, and adipose tissue-derived stem cells
Wincell Research started offering the analysis of “telomere length” in 2015. The telomere length refers to the biological age or “cell age” by Wincell Research. Knowing the biological age can help us efficiently manage and reduce risk factors causing degenerative conditions or premature aging. In the same year, we started offering the cultivation service of “fibroblast cells” and “adipose tissue-derived mesenchymal stem cells.” Although both cell types play a vital role in anti-aging medicine, a clinical study has shown that adipose tissue-derived stem cells are safe for healing the stroke that may lead to paralysis.
Umbilical cord tissue-derived stem cells
Wincell Research started offering the cultivation service of “umbilical cord tissue-derived mesenchymal stem cells” in 2014. These stem cells have become increasingly popular in regenerative medicine, with numerous studies supporting their safety for medical applications and their potential in therapy, rehabilitation, and treatment of various degenerative conditions or diseases.
Stem cells for knee osteoarthritis therapy
Wincell Research supported and participated in a clinical research project entitled “Stem Cells for Knee Osteoarthritis Therapy,” led by a team of doctors and researchers from the Stem Cell Research and Development for Medical Application Unit, Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University.
Joining a research project and publishing its derived results in the Journal of Thai Traditional and Alternative Medicine
Wincell Research collaborated on a research project with doctors and researchers from Rajavithi Hospital, Ramathibodi Hospital, and Faculty of Pharmacy – Rangsit University, entitled “The effects of cytokine-induced killer cells in the treatment of cholangiocarcinoma.” Derived results were published in the “Journal of Thai Traditional and Alternative Medicine.” Read more
Launching natural killer (NK) cell activity test service
“NK cells” play a crucial role in the innate immune system, primarily responsible for eliminating foreign bodies, including infected and abnormal cells, like cancer cells. NK cell activity can serve as another indicator reflecting our health status. Wincell Research has been offering the analysis of NK cell activity using globally recognized technology since 2012.
Granted with a research fund from the National Innovation Agency
Wincell Research was granted financial support from the National Innovation Agency, Ministry of Higher Education, Science, Research, and Innovation to conduct the “Cellular Therapeutic Technology for Cancer Treatment” project.
Immune cells for ovarian cancer treatment
Wincell Research supported and participated in clinical research on “Immune cells for ovarian cancer treatment,” led by a team of doctors and researchers at Rajavithi Hospital, Department of Medical Services, Ministry of Public Health.
Laboratory standards (Good Laboratory Practise)
Wincell Research participated in training on “Good Laboratory Practice Laboratory Standards” by a team of experts in managing and setting laboratory standards from Germany.
Granted with a research fund from the National Science and Technology Development Agency.
Wincell Research was granted financial support from the National Science and Technology Development Agency (NSTDA), Ministry of Higher Education, Science, Research, and Innovation to establish a laboratory that meets the highest standards and quality.
Establishing Wincell Research laboratory
A team of doctors, researchers, and experts in medical biotechnology and cell therapy collaboratively established the Wincell Research Laboratory.
